Solubilities of Betulinic Acid in Thirteen Organic Solvents at Different Temperatures

被引：58

作者：

Cheng, Yong ^{[1
]}

Shao, Yundong ^{[2
]}

Yan, Weidong ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China

[2] Skyherb Ingredients, Anji 313300, Peoples R China

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2011年 / 56卷 / 12期

关键词：

IN-VITRO; DERIVATIVES; HPLC;

D O I：

10.1021/je200531k

中图分类号：

O414.1 [热力学];

学科分类号：

070201 [理论物理];

摘要：

The solubilities of betulinic acid in methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, 1-pentanol, 1-hexanol, ethyl formate, ethyl acetate, butyl acetate, acetone, and tetrahydrofuran were measured by an analytical method in the temperature range of (278.2 to 318.2) K. The experimental data were correlated with a three-parameter empirical equation and UNIQUAC model, respectively. The calculated solubilities showed good agreement with the experimental data over this temperature range. Furthermore, the relation of the solubilities and the crystal habit were discussed.

引用

页码：4587 / 4591

页数：5

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