A reversible cause of hypercapnic respiratory failure - Lower motor neuronopathy associated with renal cell carcinoma

被引:17
作者
Forman, D
Rae-Grant, AD
Matchett, SC
Cowen, JS
机构
[1] Lehigh Valley Hosp Ctr, Dept Med, Allentown, PA 18102 USA
[2] Lehigh Valley Hosp Ctr, Div Neurol, Allentown, PA 18102 USA
[3] Lehigh Valley Hosp Ctr, Div Pulm & Crit Care Med, Allentown, PA 18102 USA
关键词
amyotrophic lateral sclerosis; motor neuron disease; paraneoplastic syndromes; renal cell carcinoma; respiratory insufficiency;
D O I
10.1378/chest.115.3.899
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
We describe a unique case of a patient with a reversible paraneoplastic motor neuronopathy who presented with hypercapnic respiratory failure. The patient developed progressive respiratory and limb muscle weakness until treated with removal of a renal cell carcinoma, which was followed by a complete resolution of neuromuscular symptoms. The literature of paraneoplastic motor neuronopathies is reviewed, specifically in reference to respiratory failure.
引用
收藏
页码:899 / 901
页数:3
相关论文
共 5 条
[1]   MOTOR NEURON DISEASE WITH RENAL CELL-CARCINOMA AND POSTOPERATIVE NEUROLOGIC REMISSION - CLINICOPATHOLOGIC REPORT [J].
BUCHANAN, DS ;
MALAMUD, N .
NEUROLOGY, 1973, 23 (08) :891-894
[2]   PARANEOPLASTIC MOTOR-NEURON DISEASE AND RENAL-CELL CARCINOMA - IMPROVEMENT AFTER NEPHRECTOMY [J].
EVANS, BK ;
FAGAN, C ;
ARNOLD, T ;
DROPCHO, EJ ;
OH, SJ .
NEUROLOGY, 1990, 40 (06) :960-962
[3]   Motor neuron syndromes in cancer patients [J].
Forsyth, PA ;
Dalmau, J ;
Graus, F ;
Cwik, V ;
Rosenblum, MK ;
Posner, JB .
ANNALS OF NEUROLOGY, 1997, 41 (06) :722-730
[4]  
MITCHELL M, 1979, BRIT MED J, V2, P176
[5]   LYMPHOMA, MOTOR-NEURON DISEASES, AND AMYOTROPHIC-LATERAL-SCLEROSIS [J].
YOUNGER, DS ;
ROWLAND, LP ;
LATOV, N ;
HAYS, AP ;
LANGE, DJ ;
SHERMAN, W ;
INGHIRAMI, G ;
PESCE, MA ;
KNOWLES, DM ;
POWERS, J ;
MILLER, JR ;
FETELL, MR ;
LOVELACE, RE .
ANNALS OF NEUROLOGY, 1991, 29 (01) :78-86