Reversal of antithrombotic agents

被引：58

作者：

Bauer, Kenneth A. ^{[1
,2
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA

[2] VA Boston Healthcare Syst, Boston, MA USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2012年 / 87卷

关键词：

DEEP-VEIN-THROMBOSIS; CATHETER-DIRECTED THROMBOLYSIS; QUALITY-OF-LIFE; THROMBOEMBOLIC PULMONARY-HYPERTENSION; VENOUS THROMBOSIS; POSTTHROMBOTIC SYNDROME; PHARMACOMECHANICAL THROMBECTOMY; POSTPHLEBITIC-SYNDROME; COMPRESSION STOCKINGS; RANDOMIZED TRIAL;

D O I：

10.1002/ajh.23165

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Anticoagulants are the mainstay of therapy for thromboembolic diseases. In addition to the more traditional agents, new oral anticoagulants, including dabigatran etexilate, rivaroxaban, and apixaban, have been shown to be effective across several indications. Bleeding is a serious complication associated with any anticoagulant, but many of the traditional parenteral and new oral agents do not currently have specific antidotes. This review describes available and future options for the reversal of the effects of anticoagulants, in particular the new oral agents and discusses current management strategies for bleeding events in clinical practice. Am. J. Hematol. 87: S119-S126, 2012. (C) 2012 Wiley Periodicals, Inc.

引用

页码：S119 / S126

页数：8

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