Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart

被引：28

作者：

Lebeau, J

Neviere, R

Cotelle, R ^{[1
]}

机构：

[1] Univ Sci & Tech Lille Flandres Artois, Equipe Polyphenols, Lab Chim Organ & Macromol, UPRESA 8009, F-59655 Villeneuve Dascq, France

[2] Fac Med Lille, Dept Physiol, F-59000 Lille, France

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0960-894X(00)00589-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three newly synthesised lipid peroxidation inhibitors (7, 11, 14) were evaluated for their effects on myocardial functional recovery during reperfusion after 30 min global ischemia in isolated rat hearts. The flavonoid compounds (7, 11, 14, rutin) reduce ischemia/reperfusion-induced cardiac dysfunction. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：23 / 27

页数：5

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