Synchrony: A neural correlate of somatosensory attention

被引:33
作者
Roy, A.
Steinmetz, P. N.
Hsiao, S. S.
Johnson, K. O.
Niebur, E. [1 ]
机构
[1] Johns Hopkins Univ, Zanvyl Krieger Mind Brain Inst, Baltimore, MD 21218 USA
[2] Arizona State Univ, Fulton Sch Engn, Harrington Bioengn, Tempe, AZ USA
关键词
D O I
10.1152/jn.00522.2006
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We investigated whether synchrony between neuronal spike trains is affected by the animal's attentional state. Cross-correlation functions between pairs of spike trains in the second somatosensory cortex (SII) of three macaque monkeys trained to switch attention between a visual task and a tactile task were computed. We previously showed that the majority of recorded neuron pairs (66%) in SII cortex fire synchronously while the animals performed either task and that in a subset of neuron pairs (17%), the degree of synchrony was affected by the animal's attentional state. Of the neuron pairs that showed changes in synchrony with attention, about 80% showed increased synchrony when the animal attended to the tactile stimulus. Here, we show that peak correlation typically occurred at a delay <25 ms; most commonly the delay was close to zero. Half-widths of the correlation peaks were distributed between a few milliseconds and hundreds of milliseconds, with the majority lying <100 ms and the mode of the distribution around 20 - 30 ms. Maximal change in synchrony occurred mainly during the periods when the stimulus was present, and synchrony usually increased when attention was on the tactile stimulus. If periods of elevated firing rates around the motor response times were removed from the analysis, the percentage of pairs that changed the degree of synchrony with attention more than doubled ( from 35 to 72%). The observed effects did not depend on details of the statistical criteria or of the time window used in the analysis.
引用
收藏
页码:1645 / 1661
页数:17
相关论文
共 78 条
[1]   SPATIOTEMPORAL FIRING PATTERNS IN THE FRONTAL-CORTEX OF BEHAVING MONKEYS [J].
ABELES, M ;
BERGMAN, H ;
MARGALIT, E ;
VAADIA, E .
JOURNAL OF NEUROPHYSIOLOGY, 1993, 70 (04) :1629-1638
[2]  
Abeles M., 1982, LOCAL CORTICAL CIRCU, DOI DOI 10.1007/978-3-642-81708-3
[3]   DYNAMICS OF NEURONAL FIRING CORRELATION - MODULATION OF EFFECTIVE CONNECTIVITY [J].
AERTSEN, AMHJ ;
GERSTEIN, GL ;
HABIB, MK ;
PALM, G .
JOURNAL OF NEUROPHYSIOLOGY, 1989, 61 (05) :900-917
[4]   DEPENDENCE OF CORTICAL PLASTICITY ON CORRELATED ACTIVITY OF SINGLE NEURONS AND ON BEHAVIORAL CONTEXT [J].
AHISSAR, E ;
VAADIA, E ;
AHISSAR, M ;
BERGMAN, H ;
ARIELI, A ;
ABELES, M .
SCIENCE, 1992, 257 (5075) :1412-1415
[5]   Object-based attention and occlusion: Evidence from normal participants and a computational model [J].
Behrmann, M ;
Zemel, RS ;
Mozer, MC .
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-HUMAN PERCEPTION AND PERFORMANCE, 1998, 24 (04) :1011-1036
[6]   THE EFFECT OF SYNCHRONIZED INPUTS AT THE SINGLE NEURON LEVEL [J].
BERNANDER, O ;
KOCH, C ;
USHER, M .
NEURAL COMPUTATION, 1994, 6 (04) :622-641
[7]   FAST FRONTO-PARIETAL RHYTHMS DURING COMBINED FOCUSED ATTENTIVE BEHAVIOR AND IMMOBILITY IN CAT - CORTICAL AND THALAMIC LOCALIZATIONS [J].
BOUYER, JJ ;
MONTARON, MF ;
ROUGEUL, A .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1981, 51 (03) :244-252
[8]   Slow covariations in neuronal resting potentials can lead to artefactually fast cross-correlations in their spike trains [J].
Brody, CD .
JOURNAL OF NEUROPHYSIOLOGY, 1998, 80 (06) :3345-3351
[9]  
Burton H, 2000, SOMATOSENS MOT RES, V17, P213
[10]   Tactile-spatial and cross-modal attention effects in the second somatosensory and 7b cortical areas of rhesus monkeys [J].
Burton, H ;
Sinclair, RJ ;
Hong, SY ;
Pruett, JR ;
Whang, KC .
SOMATOSENSORY AND MOTOR RESEARCH, 1997, 14 (04) :237-267