Isolation of adriatoxin, a new analogue of yessotoxin from mussels of the Adriatic sea

被引:85
作者
Ciminiello, P
Fattorusso, E
Forino, M
Magno, S
Poletti, R
Viviani, R
机构
[1] Univ Naples Federico 2, Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy
[2] Ctr Ric Marine, I-47042 Cesenatico, FO, Italy
[3] Univ Bologna, Sez Biochim Vet, Dipartimento Biochim, I-40064 Ozzano Dell Emilia, Bologna, Italy
关键词
Diarrhetic Shellfish Poisoning; DSP; adriatoxin; ATX;
D O I
10.1016/S0040-4039(98)01945-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Diarrhetic shellfish toxin composition in the hepatopancreas of mussels from northern Adriatic sea was investigated. Along with yessotoxin (YTX), homoyessotoxin (homoYTX) and 45-hydroxyyessotoxin (45-OHYTX), identified by comparison of their chromatographic and spectral properties with those reported in the literature, we isolated a new analogue of YTX, adriatoxin (ATX), whose structure was determined on the basis of spectral evidence. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:8897 / 8900
页数:4
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