Physiological evaluation of a rabbit kidney perfused with VS41A

被引：17

作者：

Arnaud, FG

Khirabadi, B

Fahy, GM

机构：

[1] USN, Med Res Ctr, Resuscitat Med Program, Silver Spring, MD 20910 USA

[2] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA

[3] 21st Century Med, Rancho Cucamonga, CA 91730 USA

来源：

CRYOBIOLOGY | 2003年 / 46卷 / 03期

关键词：

cryopreservation; machine-perfused kidney; dimethyl sulfoxide; formamide; propylene glycol; isolated perfused kidney; VS55;

D O I：

10.1016/S0011-2240(03)00045-2

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

The current report compares the renal physiological impact of a standard vitrification solution, VS41A, as measured by normothermic blood perfusion, to the physiological effects of VS4, a related but more dilute vitrification solution previously shown to be consistently compatible with life support function of transplanted rabbit kidneys. VS41A, which allows survival of only about half of the kidneys perfused with it, also appeared to be more damaging than VS4 based on in vitro functional indices and histology in one rabbit kidney so evaluated. (C) 2003 Elsevier Science (USA). All rights reserved.

引用

页码：289 / 294

页数：6

共 10 条

[1]

Normothermic blood perfusion of isolated rabbit kidneys -: II.: In vitro evaluation of renal function followed by orthotopic transplantation [J].