The first steps in adaptive evolution

被引：9

作者：

Bull, JJ ^{[1
]}

Otto, SP

机构：

[1] Univ Texas, Sect Integrat Biol, Austin, TX 78712 USA

[2] Univ Texas, Inst Mol & Cellular Biol, Austin, TX 78712 USA

[3] Univ British Columbia, Dept Zool, Vancouver, BC V6T 1Z4, Canada

来源：

NATURE GENETICS | 2005年 / 37卷 / 04期

关键词：

D O I：

10.1038/ng0405-342

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The first empirical test of an evolutionary theory provides support for a mutational landscape model underlying the process of adaptation. The study shows that it is possible to predict at least the first step in an adaptive walk and also shows the importance of incorporating mutation bias in the fitness effects of mutations.

引用

页码：342 / 343

页数：2

共 7 条

[1]

[Anonymous], 1991, The Causes of Molecular Evolution

[2]

Fisher R. A., 1999, The Genetical Theory of Natural Selection: A Complete Variorum Edition

[3]

GILLESPIE JH, 1984, EVOLUTION, V38, P1116, DOI 10.1111/j.1558-5646.1984.tb00380.x

[4] A SIMPLE STOCHASTIC GENE SUBSTITUTION MODEL [J].