A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster

被引：84

作者：

Berry, JD

Petersen, KL

机构：

[1] UCSF, Pain Clin Res Ctr, Dept Neurol, San Francisco, CA 94115 USA

[2] NW Univ, Feinberg Sch Med, Chicago, IL USA

来源：

NEUROLOGY | 2005年 / 65卷 / 03期

关键词：

D O I：

10.1212/01.WNL.0000168259.94991.8a

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.

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页码：444 / 447

页数：4

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