Collaborative consensus for optimized multilocus sequence typing of Candida albicans

被引:161
作者
Bougnoux, ME
Tavanti, A
Bouchier, C
Gow, NAR
Magnier, A
Davidson, AD
Maiden, MCJ
d'Enfert, C
Odds, FC [1 ]
机构
[1] Univ Aberdeen, Dept Mol & Cell Biol, Inst Med Sci, Aberdeen AB25 2ZD, Scotland
[2] Univ Oxford, Peter Medawar Bldg Pathogen Res, Oxford, England
[3] Univ Oxford, Dept Zool, Oxford, England
[4] Inst Pasteur, CNRS URA 2172, Unite Biol & Pathogen Fong, Paris, France
[5] Univ Versailles, Hop Ambroise Pare, Microbiol Serv, Lab Parasitol Mycol, Boulogne, France
基金
英国惠康基金;
关键词
D O I
10.1128/JCM.41.11.5265-5266.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A panel of 86 different Candida albicans isolates was subjected to multilocus sequence typing (MLST) in two laboratories to obtain sequence data for 10 published housekeeping gene fragments. Analysis of data for all possible combinations of five, six, seven, eight, and nine of the fragments showed that a set comprising the fragments AAT1a,ACC1,ADP1, MPIA, SYA1, VPS13, and ZWF1b was the smallest that yielded 86 unique diploid sequence types for the 86 isolates. This set is recommended for future MLST with C. albicans.
引用
收藏
页码:5265 / 5266
页数:2
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