Bacterial flagella and type III secretion systems

被引：71

作者：

Aizawa, S ^{[1
]}

机构：

[1] Teikyo Univ, Dept Biosci, Utsunomiya, Tochigi 3208551, Japan

来源：

FEMS MICROBIOLOGY LETTERS | 2001年 / 202卷 / 02期

关键词：

flagellum; type III secretion system; needle complex; protein secretion; homology search; instability index;

D O I：

10.1111/j.1574-6968.2001.tb10797.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Certain classes of pathogenic bacteria secrete virulence proteins in a Sec-independent manner, by a mechanism known as type III secretion. The main body of the export apparatus specific for virulence proteins is identified as a needle complex, which has a similar structural organization to flagella. The two structures share several proteins with highly homologous amino acid sequences. Even where the sequence identity is low among flagellar proteins from various species, the physico-chemical properties of each protein remain homologous. Therefore, by comparing the physico-chemical properties of unidentified proteins, it is possible to find homologs among type III secretion systems. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

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页码：157 / 164

页数：8

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