Cryo-electron microscopy of the giant mimivirus

被引：97

作者：

Xiao, CA

Chipman, PR

Battisti, AJ

Bowman, VD

Renesto, P

Raoult, D

Rossmann, MG

机构：

[1] Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA

[2] Fac Med Marseille, CNRS, UMR 6020, Unite Rickettsies, F-13385 Marseille, France

来源：

JOURNAL OF MOLECULAR BIOLOGY | 2005年 / 353卷 / 03期

关键词：

mimivirus; cryoEM; structure; nucleocytoplasmic dsDNA; unique vertex;

D O I：

10.1016/j.jmb.2005.08.060

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mimivirus is the largest known virus. Using cryo-electron microscopy, the virus was shown to be icosahedral, covered by long fibers, and appears to have at least two lipid membrarves within its protein capsid. A unique vertex, presumably for attachment and infection of the host, can be seen for particles that have a suitable orientation on the micrographs. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：493 / 496

页数：4

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