Osteoprotegerin, the bone protector, is a surprising target for β-catenin signaling

被引：40

作者：

Boyce, BF ^{[1
]}

Xing, LP

Chen, D

机构：

[1] Univ Rochester, Med Ctr, Dept Pathol & Lab Med, Rochester, NY 14642 USA

[2] Univ Rochester, Med Ctr, Ctr Musculoskeletal Res, Rochester, NY 14642 USA

来源：

CELL METABOLISM | 2005年 / 2卷 / 06期

关键词：

D O I：

10.1016/j.cmet.2005.11.011

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Osteoblasts influence bone mass by the amount of bone they synthesize and by regulating osteoclasts, the cells that degrade bone. In the December issue of Developmental Cell, Kieslinger et al. (2005) show that immature osteoblasts regulate expression of the osteoclast inhibitor, osteoprotegerin, through an early B cell factor and beta-catenin signaling.

引用

页码：344 / 345

页数：2

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