Electrical modalities beyond pacing for the treatment of heart failure

被引：8

作者：

Cornelussen, Richard N. ^{[1
]}

Splett, Vincent ^{[2
]}

Klepfer, Ruth Nicholson ^{[2
,3
]}

Stegemann, Berthold ^{[1
]}

Kornet, Lilian ^{[1
]}

Prinzen, Frits W. ^{[3
]}

机构：

[1] Medtron Bakken Res Ctr BV, Res & Technol, NL-6229 GW Maastricht, Netherlands

[2] Medtron Moundsview, CRDM, Minneapolis, MN USA

[3] Maastricht Univ, Dept Physiol, Maastricht, Netherlands

来源：

HEART FAILURE REVIEWS | 2011年 / 16卷 / 03期

关键词：

Pacing; Nervous system; (Electro) Physiology; Contractility; Heart failure; CARDIAC CONTRACTILITY MODULATION; LEFT-VENTRICULAR CONTRACTILITY; SPINAL-CORD STIMULATION; ACUTE HEMODYNAMIC-RESPONSE; REFRACTORY PERIOD; POSTEXTRASYSTOLIC POTENTIATION; MATRIX METALLOPROTEINASES; MYOCARDIAL-INFARCTION; ATRIAL-FIBRILLATION; GENE-EXPRESSION;

D O I：

10.1007/s10741-010-9206-2

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

In this review, we report on electrical modalities, which do not fit the definition of pacemaker, but increase cardiac performance either by direct application to the heart (e. g., post-extrasystolic potentiation or non-excitatory stimulation) or indirectly through activation of the nervous system (e. g., vagal or sympathetic activation). The physiological background of the possible mechanisms of these electrical modalities and their potential application to treat heart failure are discussed.

引用

页码：315 / 325

页数：11

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