Overview of protein aggregation in single, double, and triple neurodegenerative brain amyloidoses

被引:32
作者
Trojanowski, JQ [1 ]
Mattson, MP
机构
[1] Univ Penn, Sch Med, Inst Aging, Ctr Neurodegenerat Dis Res,Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
[2] NIA, Intramural Res Program, Neurosci Lab, Baltimore, MD 21224 USA
关键词
D O I
10.1385/NMM:4:1-2:1
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:1 / 5
页数:5
相关论文
共 24 条
[1]   Pharmacological prevention of Parkinson disease in Drosophila [J].
Auluck, PK ;
Bonini, NM .
NATURE MEDICINE, 2002, 8 (11) :1185-1186
[2]   Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease [J].
Auluck, PK ;
Chan, HYE ;
Trojanowski, JQ ;
Lee, VMY ;
Bonini, NM .
SCIENCE, 2002, 295 (5556) :865-868
[3]   Chaperoning brain degeneration [J].
Bonini, NM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 :16407-16411
[4]   Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases [J].
Bucciantini, M ;
Giannoni, E ;
Chiti, F ;
Baroni, F ;
Formigli, L ;
Zurdo, JS ;
Taddei, N ;
Ramponi, G ;
Dobson, CM ;
Stefani, M .
NATURE, 2002, 416 (6880) :507-511
[5]   Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions [J].
Giasson, BI ;
Duda, JE ;
Murray, IVJ ;
Chen, QP ;
Souza, JM ;
Hurtig, HI ;
Ischiropoulos, H ;
Trojanowski, JQ ;
Lee, VMY .
SCIENCE, 2000, 290 (5493) :985-989
[6]   The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases [J].
Giasson, BI ;
Ischiropoulos, H ;
Lee, VMY ;
Trojanowski, JQ .
FREE RADICAL BIOLOGY AND MEDICINE, 2002, 32 (12) :1264-1275
[7]   Initiation and synergistic fibrillization of tau and alpha-synuclein [J].
Giasson, BI ;
Forman, MS ;
Higuchi, M ;
Golbe, LI ;
Graves, CL ;
Kotzbauer, PT ;
Trojanowski, JQ ;
Lee, VMY .
SCIENCE, 2003, 300 (5619) :636-640
[8]   Amyloid, the presenilins and Alzheimer's disease [J].
Hardy, J .
TRENDS IN NEUROSCIENCES, 1997, 20 (04) :154-159
[9]   Genetic dissection of Alzheimer's disease and related dementias: Amyloid and its relationship to tau [J].
Hardy, J ;
Duff, K ;
Hardy, KG ;
Perez-Tur, J ;
Hutton, M .
NATURE NEUROSCIENCE, 1998, 1 (05) :355-358
[10]   AMYLOID DEPOSITION AS THE CENTRAL EVENT IN THE ETIOLOGY OF ALZHEIMERS-DISEASE [J].
HARDY, J ;
ALLSOP, D .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1991, 12 (10) :383-388