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Meiotic recombination hot spots and cold spots

被引：393
作者：
Petes, TD [1 ]
机构：
[1] Univ N Carolina, Dept Biol, Curriculum Genet & Mol Biol, Chapel Hill, NC 27599 USA
来源：
NATURE REVIEWS GENETICS | 2001年 / 2卷 / 05期
关键词：
D O I：
10.1038/35072078
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Meiotic recombination events are distributed unevenly throughout eukaryotic genomes. This inhomogeneity leads to distortions of genetic maps that can hinder the ability of geneticists to identify genes by map-based techniques. Various lines of evidence, particularly from studies of yeast, indicate that the distribution of recombination events might reflect, at least in part, global features of chromosome structure, such as the distribution of modified nucleosomes.
引用
收藏
页码：360 / 369
页数：10
相关论文
共 110 条
  • [1] Allen JB, 1994, GENE DEV, V8, P2416
  • [2] ALLELIC DIVERSITY AT MINISATELLITE MS205 (D16S309) - EVIDENCE FOR POLARIZED VARIABILITY
    ARMOUR, JAL
    HARRIS, PC
    JEFFREYS, AJ
    [J]. HUMAN MOLECULAR GENETICS, 1993, 2 (08) : 1137 - 1145
  • [3] MULTIPLE GLOBAL REGULATORS CONTROL HIS4 TRANSCRIPTION IN YEAST
    ARNDT, KT
    STYLES, C
    FINK, GR
    [J]. SCIENCE, 1987, 237 (4817) : 874 - 880
  • [4] Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
    Bannister, AJ
    Zegerman, P
    Partridge, JF
    Miska, EA
    Thomas, JO
    Allshire, RC
    Kouzarides, T
    [J]. NATURE, 2001, 410 (6824) : 120 - 124
  • [5] Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11
    Baudat, F
    Manova, K
    Yuen, JP
    Jasin, M
    Keeney, S
    [J]. MOLECULAR CELL, 2000, 6 (05) : 989 - 998
  • [6] Clustering of meiotic double-strand breaks on yeast chromosome III
    Baudat, F
    Nicolas, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) : 5213 - 5218
  • [7] An atypical topoisomerase II from archaea with implications for meiotic recombination
    Bergerat, A
    deMassy, B
    Gadelle, D
    Varoutas, PC
    Nicolas, A
    Forterre, P
    [J]. NATURE, 1997, 386 (6623) : 414 - 417
  • [8] Genomewide studies of histone deacetylase function in yeast
    Bernstein, BE
    Tong, JK
    Schreiber, SL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (25) : 13708 - 13713
  • [9] Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region
    Blat, Y
    Kleckner, N
    [J]. CELL, 1999, 98 (02) : 249 - 259
  • [10] DNA motif associated with meiotic double-strand break regions in Saccharomyces cerevisiae
    Blumental-Perry, A
    Zenvirth, D
    Klein, S
    Onn, I
    Simchen, G
    [J]. EMBO REPORTS, 2000, 1 (03) : 232 - 238
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