High-dose oral morphine in cancer pain management: A report of twelve cases

被引：18

作者：

Radbruch, L

Grond, S

Zech, DJ

Bischoff, A

机构：

[1] Department of Anaesthesiology, University of Cologne, Cologne

[2] Klin. Poliklin. Anaesthiol. Oper. I., Universität zu Köln, 50924 Köln

来源：

JOURNAL OF CLINICAL ANESTHESIA | 1996年 / 8卷 / 02期

关键词：

cancer pain; morphine; neuropathic pain; opioid responsiveness;

D O I：

10.1016/0952-8180(95)00201-4

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We present 12 case reports from patients treated with more than 600 mg of morphine per day. We found no ''opioid-nonresponsive pain'' under treatment with a combination of morphine and nonopioids, supplemented with coanalgesics where appropriate. Side effects of morphine therapy were controlled with adjuvant drugs. Serious adverse effects were not observed. Episodes of break-through pain, dysphagia, and dyspnea caused by far advanced cancer disease were seen frequently.

引用

页码：144 / 150

页数：7

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