Signal transduction - G proteins and small GTPases: Distant relatives keep in touch

被引:170
作者
Hall, A [1 ]
机构
[1] UCL, MRC, Mol Cell Biol Lab, London WC1E 6BT, England
[2] UCL, Dept Biochem, Canc Res Campaign Oncogene, London WC1E 6BT, England
[3] UCL, Signal Transduct Grp, London WC1E 6BT, England
关键词
D O I
10.1126/science.280.5372.2074
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:2074 / 2075
页数:2
相关论文
共 17 条
[1]   The rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation [J].
Barrett, K ;
Leptin, M ;
Settleman, J .
CELL, 1997, 91 (07) :905-915
[2]   PHOSPHOLIPASE C-BETA-1 IS A GTPASE-ACTIVATING PROTEIN FOR GQ/11, ITS PHYSIOLOGICAL REGULATOR [J].
BERSTEIN, G ;
BLANK, JL ;
JHON, DY ;
EXTON, JH ;
RHEE, SG ;
ROSS, EM .
CELL, 1992, 70 (03) :411-418
[3]   Healing of incisional wounds in the embryonic chick wing bud: Characterization of the actin purse-string and demonstration of a requirement for Rho activation [J].
Brock, J ;
Midwinter, K ;
Lewis, J ;
Martin, P .
JOURNAL OF CELL BIOLOGY, 1996, 135 (04) :1097-1107
[4]   G-ALPHA(12) AND G-ALPHA(13) STIMULATE RHO-DEPENDENT STRESS FIBER FORMATION AND FOCAL ADHESION ASSEMBLY [J].
BUHL, AM ;
JOHNSON, NL ;
DHANASEKARAN, N ;
JOHNSON, GL .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (42) :24631-24634
[5]   RGS proteins and signaling by heterotrimeric G proteins [J].
Dohlman, HG ;
Thorner, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (07) :3871-3874
[6]   Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein [J].
Glaven, JA ;
Whitehead, IP ;
Nomanbhoy, T ;
Kay, R ;
Cerione, RA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (44) :27374-27381
[7]   The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho [J].
Gohla, A ;
Harhammer, R ;
Schultz, G .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (08) :4653-4659
[8]   DRhoGEF2 encodes a member of the Db1 family of oncogenes and controls cell shape changes during gastrulation in Drosophila [J].
Häcker, U ;
Perrimon, N .
GENES & DEVELOPMENT, 1998, 12 (02) :274-284
[9]   Rho GTPases and the actin cytoskeleton [J].
Hall, A .
SCIENCE, 1998, 279 (5350) :509-514
[10]   Role of substrates and products of PI3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav [J].
Han, JW ;
Luby-Phelps, K ;
Das, B ;
Shu, XD ;
Xia, Y ;
Mosteller, RD ;
Krishna, UM ;
Falck, JR ;
White, MA ;
Broek, D .
SCIENCE, 1998, 279 (5350) :558-560