First highly enantioselective epoxidation of alkenes with aldehyde/Oxone®

被引：20

作者：

Bez, G ^{[1
]}

Zhao, CG ^{[1
]}

机构：

[1] Univ Texas, Dept Chem, San Antonio, TX 78249 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 40期

关键词：

aldehyde dioxirane; enantioselective; alkene; epoxidation; Oxone (R);

D O I：

10.1016/j.tetlet.2003.08.040

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active aldehydes have been successfully used as catalysts for asymmetric epoxidations of unfunctionalized alkenes (ee up to 94%) by using Oxone((R)) as the oxygen source. Experimental results indicate that the in-situ-generated aldehyde dioxirane is responsible for this catalytic activity. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：7403 / 7406

页数：4

共 32 条

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