Performance of the Molecular Alere i Influenza A&B Test Compared to That of the Xpert Flu A/B Assay

被引：43

作者：

Chapin, Kimberle C. ^{[1
,2
]}

Flores-Cortez, Estefany J. ^{[1
]}

机构：

[1] Rhode Isl Hosp, Dept Pathol, Lifespan Acad Med Ctr, Providence, RI 02902 USA

[2] Brown Univ, Warren Alpert Med Sch, Providence, RI 02912 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2015年 / 53卷 / 02期

关键词：

ACID AMPLIFICATION TEST;

D O I：

10.1128/JCM.02783-14

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Data on the performance of rapid molecular point-of-care use platforms for diagnosis of influenza are lacking. We validated nasopharyngeal (NP) flocked specimens in universal transport medium (UTM) and evaluated the clinical sensitivity and specificity of the Alere i influenza A&B test compared to those of the Xpert flu A/B assay. The Alere i influenza A&B test had an overall sensitivity and specificity of 93.8% and 62.5% for influenza A, respectively, and of 91.8% and 53.6% for influenza B, respectively. The poor specificity was due to influenza virus samples determined positive for both type A and B.

引用

页码：706 / 709

页数：4

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