The effect of the reconstitution medium on aggregation of lyophilized recombinant interleukin-2 and ribonuclease A

被引：36

作者：

Zhang, MZ ^{[1
]}

Pikal, K ^{[1
]}

Nguyen, T ^{[1
]}

Arakawa, T ^{[1
]}

Prestrelski, SJ ^{[1
]}

机构：

[1] AMGEN INC,AMGEN CTR,DEPT PROT CHEM,THOUSAND OAKS,CA 91320

来源：

关键词：

proteins; aggregation; reconstitution; lyophilization; additives; stability;

D O I：

10.1023/A:1016074811306

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：643 / 646

页数：4

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