Oscillations in superoxide anion release by polymorphonuclear leukocytes and its inhibition by human saliva

被引：6

作者：

Brigagao, MRPL

Colepicolo, P

机构：

[1] UNIV SAO PAULO,INST QUIM,DEPT BIOQUIM,BR-05508900 SAO PAULO,SP,BRAZIL

[2] ESCOLA FARM & ODONTOL ALFENAS,BR-37130000 ALFENAS,MG,BRAZIL

来源：

BIOLOGICAL RHYTHM RESEARCH | 1996年 / 27卷 / 03期

关键词：

polymorphonuclear leukocytes; inflammation; superoxide anion; human saliva;

D O I：

10.1076/brhm.27.3.261.12957

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

The release of superoxide anion (O-2(-)) by inflammatory polymorphonuclear leukocytes (PMN), obtained from the intraperitoneal cavity of mice, was investigated during two different times of the day. NaF-stimulated PMN at nigth-phase showed greater release of O-2(-) than at day. Addition of human saliva in the culture medium dramatically inhibits O-2(-) generation by both day- and night-phase cells. Also, the inhibitory effect of diurnal saliva on the cell activation is higher than the nocturnal saliva.

引用

页码：261 / 268

页数：8

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