A concise synthesis of the (-)-allosamizoline aminocyclopentitol based on pyridinium salt photochemistry

被引：28

作者：

Lu, HY

Mariano, PS ^{[1
]}

Lam, YF

机构：

[1] Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA

[2] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 29期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(01)00858-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The (-)-allosamizoline aminocyclopentitol was prepared by use of a route featuring pyridinium salt photochemical synthesis of the aminocyclopentene core, enzymatic desymmetrization, Wittig rearrangement to introduce the hydroxymethyl side chain, and regiocontrolled exporide ring opening. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：4755 / 4757

页数：3

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