学术探索
学术期刊
新闻热点
数据分析
智能评审

Hematopoietic stem cell transplantation for autoimmune diseases: What have we learned?

被引：61
作者：
Burt, Richard K. [1 ]
Testor, Alessandro [1 ]
Craig, Robert [2 ]
Cohen, Bruce [3 ]
Suffit, Robert [3 ]
Barr, Walter [4 ]
机构：
[1] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Immunotherapy, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Gastroenterol, Chicago, IL 60611 USA
[3] Northwestern Univ, Feinberg Sch Med, Dept Neurol, Chicago, IL 60611 USA
[4] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Rheumatol, Chicago, IL 60611 USA
来源：
JOURNAL OF AUTOIMMUNITY | 2008年 / 30卷 / 03期
关键词：
hematopoietic stem cell transplantation (HSCT); autologous HSCT; animal models; human trials;
D O I：
10.1016/j.jaut.2007.12.010
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Numerous individuals and institutions throughout the world have contributed to the development of hematopoietic stem cell transplantation (HSCT) for autoimmune diseases. In this review, we will summarize what we have learned at our own institution (Northwestern University), and how it has guided our therapy. An emphasis will be placed on both the scientific basis for the development of autologous hematopoietic stem cell transplantation and a summary of the data in a variety of human diseases. (C) 2008 Published by Elsevier Ltd.
引用
收藏
页码：116 / 120
页数：5
相关论文
共 57 条
  • [1] Balancing autoaggressive and protective T cell responses
    Abbas, Abul K.
    Lohr, Jens
    Knoechel, Birgit
    [J]. JOURNAL OF AUTOIMMUNITY, 2007, 28 (2-3) : 59 - 61
  • [2] Bone marrow stem cell transplant into intra-bone cavity prevents type 2 diabetes: Role of heme oxygenase-adiponectin
    Abraham, Nader G.
    Li, Ming
    Vanella, Luca
    Peterson, Stephen J.
    Ikehara, Susumu
    Asprinio, David
    [J]. JOURNAL OF AUTOIMMUNITY, 2008, 30 (03) : 128 - 135
  • [3] Anti-recoverin antibodies induce an increase in intracellular calcium, leading to apoptosis in retinal cells
    Adamus, G
    Webb, S
    Shiraga, S
    Duvoisin, RM
    [J]. JOURNAL OF AUTOIMMUNITY, 2006, 26 (02) : 146 - 153
  • [4] Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitus
    Anaya, Juan-Manuel
    Castiblanco, John
    Tobon, Gabriel J.
    Garcia, Jorge
    Abad, Veronica
    Cuervo, Hector
    Velasquez, Alejandro
    Angel, Ivan D.
    Vega, Patricia
    Arango, Alvaro
    [J]. JOURNAL OF AUTOIMMUNITY, 2006, 26 (03) : 208 - 214
  • [5] Naturally occurring B-cell autoreactivity: A critical overview
    Avrameas, Stratis
    Ternynck, Therese
    Tsonis, Ioannis A.
    Lymberi, Peggy
    [J]. JOURNAL OF AUTOIMMUNITY, 2007, 29 (04) : 213 - 218
  • [6] Suppression of activin A in autoimmune lung disease associated with anti-GM-CSF
    Bonfield, TL
    Barna, BP
    John, N
    Malur, A
    Culver, DA
    Kavura, MS
    Thomassen, MJ
    [J]. JOURNAL OF AUTOIMMUNITY, 2006, 26 (01) : 37 - 41
  • [7] The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases
    Boren, Eric J.
    Cheema, Gurtej S.
    Naguwa, Stanley M.
    Ansari, Aftab A.
    Gershwin, M. Eric
    [J]. JOURNAL OF AUTOIMMUNITY, 2008, 30 (1-2) : 90 - 98
  • [8] Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission
    Brown, Jennifer R.
    Feng, Yang
    Gribben, John G.
    Neuberg, Donna
    Fisher, David C.
    Mauch, Peter
    Nadler, Lee M.
    Freedman, Arnold S.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2007, 13 (09) : 1057 - 1065
  • [9] Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases - The evolution from myeloablative to lymphoablative transplant regimens
    Burt, Richard K.
    Marmont, Alberto
    Oyama, Yu
    Slavin, Shimon
    Arnold, Renate
    Hiepe, Falk
    Fassas, Athanasios
    Snowden, John
    Schuening, Friedrich
    Myint, Han
    Patel, Dhavalkumar D.
    Collier, David
    Heslop, Helen
    Krance, Robert
    Statkute, Laisvyde
    Verda, Larissa
    Traynor, Ann
    Kozak, Tomas
    Hintzen, Rogier Q.
    Rose, John W.
    Voltarelli, Julio
    Loh, Yvonne
    Territo, Mary
    Cohen, Bruce A.
    Craig, Robert M.
    Varga, John
    Barr, Walter G.
    [J]. ARTHRITIS AND RHEUMATISM, 2006, 54 (12): : 3750 - 3760
  • [10] Nonmyeloablative hematopoietic stem cell transplantation for systemic lupus erythematosus
    Burt, RK
    Traynor, A
    Statkute, L
    Barr, WG
    Rosa, R
    Schroeder, J
    Verda, L
    Krosnjar, N
    Quigley, K
    Yaung, K
    Villa, M
    Takahashi, M
    Jovanovic, B
    Oyama, Y
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 295 (05): : 527 - 535
123456