Analytical theory of susceptibility induced NMR signal dephasing in a cerebrovascular network

被引:85
作者
Kiselev, VG [1 ]
Posse, S
机构
[1] Res Ctr Julich GmbH, Inst Med, D-52425 Julich, Germany
[2] Inst Phys, Minsk 220602, BELARUS
关键词
D O I
10.1103/PhysRevLett.81.5696
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
A deterministic analytical model which describes the time course of NMR signal relaxation in media where the magnetic field is perturbed by stochastic low-density inclusions having one-dimensional extent is developed. Both static and diffusion dephasing mechanisms are included. The model is applied to a simulation of a living tissue where the inclusions are identified with blood microvessels. This application is a ground for quantitation of signal changes during brain activation measured by functional magnetic resonance imaging. The results are consistent with previous Monte Carlo simulations.
引用
收藏
页码:5696 / 5699
页数:4
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