An overview of the determinants of CCR5 and CXCR4 co-receptor function

被引:111
作者
Dragic, T [1 ]
机构
[1] Yeshiva Univ Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10461 USA
关键词
D O I
10.1099/0022-1317-82-8-1807
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
[No abstract available]
引用
收藏
页码:1807 / 1814
页数:8
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  • [1] HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: Independence from G protein signaling and importance of coreceptor downmodulation
    Alkhatib, G
    Locati, M
    Kennedy, PE
    Murphy, PM
    Berger, EA
    [J]. VIROLOGY, 1997, 234 (02) : 340 - 348
  • [2] CC chemokine receptor 5-mediated signaling and HIV-1 co-receptor activity share common structural determinants - Critical residues in the third extracellular loop support HIV-1 fusion
    Alkhatib, G
    Ahuja, SS
    Light, D
    Mummidi, S
    Berger, EA
    Ahuja, SK
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (32) : 19771 - 19776
  • [3] HIV coreceptor downregulation as antiviral principle: SDF-1 alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication
    Amara, A
    LeGall, S
    Schwartz, O
    Salamero, J
    Montes, M
    Loetscher, P
    Baggiolini, M
    Virelizier, JL
    ArenzanaSeisdedos, F
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (01) : 139 - 146
  • [4] T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure
    Arakaki, R
    Tamamura, H
    Premanathan, M
    Kanbara, K
    Ramanan, S
    Mochizuki, K
    Baba, M
    Fujii, N
    Nakashima, H
    [J]. JOURNAL OF VIROLOGY, 1999, 73 (02) : 1719 - 1723
  • [5] Multiple extracellular elements of CCR5 and HIV-1 entry: Dissociation from response to chemokines
    Atchison, RE
    Gosling, J
    Monteclaro, FS
    Franci, C
    Digilio, L
    Charo, IF
    Goldsmith, MA
    [J]. SCIENCE, 1996, 274 (5294) : 1924 - 1926
  • [6] A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
    Baba, M
    Nishimura, O
    Kanzaki, N
    Okamoto, M
    Sawada, H
    Iizawa, Y
    Shiraishi, M
    Aramaki, Y
    Okonogi, K
    Ogawa, Y
    Meguro, K
    Fujino, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (10) : 5698 - 5703
  • [7] Human immunodeficiency virus (HIV) envelope binds to CXCR4 independently of CD4, and binding can be enhanced by interaction with soluble CD4 or by HIV envelope deglycosylation
    Bandres, JC
    Wang, QF
    O'Leary, J
    Baleaux, F
    Amara, A
    Hoxie, JA
    Zolla-Pazner, S
    Gorny, MK
    [J]. JOURNAL OF VIROLOGY, 1998, 72 (03) : 2500 - 2504
  • [8] Patterns of CCR5, CXCR4, and CCR3 usage by envelope glycoproteins from human immunodeficiency virus type 1 primary isolates
    Bazan, HA
    Alkhatib, G
    Broder, CC
    Berger, EA
    [J]. JOURNAL OF VIROLOGY, 1998, 72 (05) : 4485 - 4491
  • [9] The CCR5 deletion mutation fails to protect against multiple sclerosis
    Bennetts, BH
    Teutsch, SM
    Buhler, MM
    Heard, RNS
    Stewart, GJ
    [J]. HUMAN IMMUNOLOGY, 1997, 58 (01) : 52 - 59
  • [10] A new classification for HIV-1
    Berger, EA
    Doms, RW
    Fenyö, EM
    Korber, BTM
    Littman, DR
    Moore, JP
    Sattentau, QJ
    Schuitemaker, H
    Sodroski, J
    Weiss, RA
    [J]. NATURE, 1998, 391 (6664) : 240 - 240