Kinetic studies of protein folding using NMR spectroscopy

被引：77

作者：

Dobson, CM

Hore, PJ

机构：

[1] Univ Oxford, Oxford Ctr Mol Sci, New Chem Lab, Oxford OX1 3QR, England

[2] Univ Oxford, Phys & Theoret Chem Lab, Oxford OX1 3QR, England

来源：

NATURE STRUCTURAL BIOLOGY | 1998年 / 5卷 / Suppl 7期

基金：

英国惠康基金;

关键词：

D O I：

10.1038/744

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent progress has advanced our abilities to use NMR spectroscopy to follow - in real time - the structural and dynamic changes taking place during protein Folding.

引用

页码：504 / 507

页数：4

共 27 条

[1] Protein folding monitored at individual residues during a two-dimensional NMR experiment [J].

Balbach, J ;

Forge, V ;

Lau, WS ;

vanNuland, NAJ ;

Brew, K ;

Dobson, CM .

SCIENCE, 1996, 274 (5290) :1161-1163

[2] Detection of residue contacts in a protein folding intermediate [J].

Balbach, J ;

Forge, V ;

Lau, WS ;

Jones, JA ;

VanNuland, NAJ ;

Dobson, CM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (14) :7182-7185

[3] FOLLOWING PROTEIN-FOLDING IN REAL-TIME USING NMR-SPECTROSCOPY [J].

BALBACH, J ;

FORGE, V ;

VANNULAND, NAJ ;

WINDER, SL ;

HORE, PJ ;

DOBSON, CM .

NATURE STRUCTURAL BIOLOGY, 1995, 2 (10) :865-870

[4] PULSED H/D-EXCHANGE STUDIES OF FOLDING INTERMEDIATES [J].

BALDWIN, RL .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1993, 3 (01) :84-91

[5] Real-time NMR investigations of triple-helix folding and collagen folding diseases [J].

Baum, J ;

Brodsky, B .

FOLDING & DESIGN, 1997, 2 (04) :R53-R60

[6] A PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR-POLARIZATION STUDY OF DENATURED STATES OF LYSOZYME [J].

BROADHURST, RW ;

DOBSON, CM ;

HORE, PJ ;

RADFORD, SE ;

REES, ML .

BIOCHEMISTRY, 1991, 30 (02) :405-412

[7]

Dobson CM, 1998, ANGEW CHEM INT EDIT, V37, P868, DOI 10.1002/(SICI)1521-3773(19980420)37:7<868::AID-ANIE868>3.0.CO

[8]

2-H

[9] UNDERSTANDING HOW PROTEINS FOLD - THE LYSOZYME STORY SO FAR [J].

DOBSON, CM ;

EVANS, PA ;

RADFORD, SE .

TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (01) :31-37

[10] Equilibrium NMR studies of unfolded and partially folded proteins [J].

Dyson, HJ ;

Wright, PE .

NATURE STRUCTURAL BIOLOGY, 1998, 5 (Suppl 7) :499-503

← 1 2 3 →