Fatal human rabies caused by European bat lyssavirus type 2a infection in Scotland

被引：49

作者：

Nathwani, D

McIntyre, PG

White, K

Shearer, AJ

Reynolds, N

Walker, D

Orange, GV

Fooks, AR

机构：

[1] Univ Dundee, Ninewells Hosp & Med Sch, Dept Infect Dis, Infect Unit, Dundee DD1 9SY, Scotland

[2] Univ Dundee, Ninewells Hosp & Med Sch, Dept Virol, Dundee DD1 9SY, Scotland

[3] Univ Dundee, Ninewells Hosp & Med Sch, Dept Neurol, Dundee DD1 9SY, Scotland

[4] Univ Dundee, Ninewells Hosp & Med Sch, Dept Anaesthesia, Dundee DD1 9SY, Scotland

[5] Univ Dundee, Ninewells Hosp & Med Sch, Dept Intens Care, Dundee DD1 9SY, Scotland

[6] Univ Dundee, Ninewells Hosp & Med Sch, Dept Med, Dundee DD1 9SY, Scotland

[7] Univ Dundee, Ninewells Hosp & Med Sch, Dept Microbiol, Dundee DD1 9SY, Scotland

[8] Tayside Hlth Board, Dept Publ Hlth, Dundee, Scotland

[9] Vet Labs Agcy, Diagnost Grp, Surrey, England

来源：

CLINICAL INFECTIOUS DISEASES | 2003年 / 37卷 / 04期

关键词：

D O I：

10.1086/376641

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We wish to report the first recorded case of indigenous human rabies caused by a bat bite in the United Kingdom in 100 years. This instructive case report highlights a number of key lessons: first, bites from insectivorous bats indiginous to the United Kingdom can cause rabies in humans; second, rabies immunization is essential for bat-handlers, and postexposure treatment for rabies is essential for patients bitten by bats; third, patients able to give a history who present with acute flaccid paralysis and/or presumptive viral encephalitis should be asked if they have been bitten by bats, irrespective of travel history, or this history should be obtained from family or friends; fourth, antemortem diagnosis of bat rabies (EBLV type 2a infection) in humans is possible using RT-PCR.

引用

页码：598 / 601

页数：4

共 18 条

[1] Evidence of two Lyssavirus phylogroups with distinct pathogenicity and immunogenicity [J].