Synthesis and properties of oligonucleotides involving a perylene unit linked to a 2′-deoxyribose residue

被引：4

作者：

Aubert, Y

Asseline, U

机构：

[1] Univ Orleans, Ctr Biophys Mol, UPR 4301, CNRS, F-45071 Orleans 02, France

[2] INSERM, F-45071 Orleans, France

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期

关键词：

oligonucleotide-perylene conjugates; perylene-2 '-deoxyribose unit; synthesis; binding properties;

D O I：

10.1081/NCN-120022841

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We report here the synthesis and binding properties of oligonucleotides involving a perylene unit linked to the anomeric position of a 2'-deoxyribose residue. Both anomers were separated and incorporated separately at either the 5'-end or the internal position of a pyrimidine sequence. In any case the presence of the perylene unit stabilizes the complexes formed with either the single or the double-stranded target.

引用

页码：1223 / 1225

页数：3

共 7 条

[1]

Synthesis and binding properties of perylene-oligo-2′-deoxyribonucleotide conjugates [J].