Human testis specifically expresses a homologue of the rodent T lymphocytes RT6 mRNA

被引：24

作者：

Levy, I

Wu, YQ

Roeckel, N

Bulle, F

Pawlak, A

Siegrist, S

Mattei, MG

Guellaen, G

机构：

[1] HOP HENRI MONDOR,U INSERM 99,F-94010 CRETEIL,FRANCE

[2] HOP ENFANTS LA TIMONE,U INSERM 406,F-13385 MARSEILLE,FRANCE

来源：

FEBS LETTERS | 1996年 / 382卷 / 03期

关键词：

human testis; mono ADP-ribosyl transferase; RT6; chromosome; 4; diabetes mellitus;

D O I：

10.1016/0014-5793(96)00183-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A human homologue of the rodent T cell mono ADP-ribosyl transferase RT6 mRMA was identified by a systematic analysis of human testis transcripts. This messenger encodes for a precursor protein of 367 aa (MW: 41.5 kDa) which exhibits a peptide signal, consensus domains for mono ADP-ribosyl transferase and a C-terminal part characteristic of glycophosphatidyl inositol anchored protein. This mRNA, transcribed from a gene localized in 4q13-q21, is not expressed in white blood cells but is specific for human testis in which it is likely to correspond to a new ADP-ribosyl transferase.

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收藏

页码：276 / 280

页数：5

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