Electrochemiluminescent behavior of melatonin and its important derivatives in the presence of Ru(bpy)32+

被引:31
作者
Wu, XP
Huang, FX
Duan, JP
Chen, GN [1 ]
机构
[1] Fuzhou Univ, Dept Chem, Fujian 350002, Peoples R China
[2] Fuzhou Univ, Analyt & Testing Ctr, Fujian 350002, Peoples R China
关键词
melatonin and its derivatives; electrochemilurninescence; Ru(bpy)(3)(2+);
D O I
10.1016/j.talanta.2004.09.003
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Melatonin and some of its important derivatives were found to be able to enhance the ECL of Ru(bpy)(3)(2+) in an alkaline Britton-Robinson buffer solution. The Optimum conditions for the enhanced ECL, such as the selection of applied potential mode, type of buffer solution, pH effect and effect of Ru(bpy)(3)(2+) concentration have been investigated in detail in this paper. Under the optimum conditions, the enhanced ECL is linear with the concentration of melatonin and its derivatives over the wide range, and the detection limit for these compounds was found to be in the ran-e of 5.0 x 10(-8) to 1.0 x 10(-10) mol L-1. The proposed procedure was applied for the determination of drug tablets with recoveries of 85-93%. A possible mechanism for the enhanced ECL of Ru(bpy)(3)(2+) by melatonin and its derivatives was proposed. and the relationship between molecular structure of melatonin and its derivatives and the enhanced ECL behavior was also discussed. (c) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:1279 / 1285
页数:7
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