Studies of the multifaceted mast cell response to bacteria

被引:19
作者
McLachlan, JB [1 ]
Abraham, SN
机构
[1] Duke Univ, Med Ctr, Dept Pathol, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Microbiol, Durham, NC 27710 USA
关键词
D O I
10.1016/S1369-5274(00)00200-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The concept of mast cells as playing a critical and multifaceted role in immune defense against pathogens is new, and effective ways to study and validate this notion are required. Recently, a number of approaches have been described that can be used to study the molecular aspects of mast cell recognition of pathogens, and of specific mast cell responses, such as mediator release, bacterial endocytosis and mast cell migration, to pathogens.
引用
收藏
页码:260 / 266
页数:7
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