Effect of Intense Pulsed Light on Rat Skin

被引：9

作者：

Cho, Eun Byul ^{[1
]}

Park, Hoon ^{[2
]}

Park, Eun Joo ^{[1
]}

Kwon, In Ho ^{[1
]}

Kim, Sang Seok ^{[3
]}

Kim, Kwang Ho ^{[1
]}

Kim, Kwang Joong ^{[1
]}

Park, Hye Rim ^{[4
]}

机构：

[1] Hallym Univ, Dept Dermatol, Coll Med, Anyang 431070, Gyeonggi Do, South Korea

[2] Catholic Univ Korea, Dept Dermatol, Coll Med, Seoul, South Korea

[3] Hallym Univ, Dept Dermatol, Coll Med, Kangdong Sacred Heart Hosp, Seoul, South Korea

[4] Hallym Univ, Dept Pathol, Coll Med, Anyang 431070, Gyeonggi Do, South Korea

来源：

DERMATOLOGIC SURGERY | 2012年 / 38卷 / 03期

关键词：

PHOTOTHERMAL SCLEROSIS; DYE-LASER; LEG VEINS; REJUVENATION;

D O I：

10.1111/j.1524-4725.2011.02213.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

BACKGROUND Intense pulsed light (IPL) is widely used in treating skin conditions and has been reported to increase collagen and elastic fibers without damaging the epidermis. OBJECTIVE To evaluate the effect of variation in the number of passes and intervals of IPL treatments on photorejuvenation in rats. MATERIALS AND METHODS Groups of two rats each were exposed to two or four passes of an IPL source using a fluence of 30 J/cm 2 and a cut-off filter of 560 nm at 1-or 3-week intervals. The collagen and elastic fiber content in stained tissue biopsies and the thickness of the collagen fibers of IPL-irradiated and unexposed skin regions were compared. RESULTS Collagen distribution and collagen fiber diameter was in IPL-irradiated than in control regions. The number of passes did not significantly affect the collagen fiber thickness, but the collagen fibers from the 3-week-interval groups were thicker than those of the 1-week-interval groups (p <.001). CONCLUSION IPL increased dermal collagen fibers and collagen fiber diameter, suggesting efficacy in photorejuvenation and wrinkle reduction.

引用

页码：430 / 436

页数：7

共 22 条

[1]

TREATMENT OF KELOID STERNOTOMY SCARS WITH 585 NM FLASHLAMP-PUMPED PULSED-DYE LASER [J].