Additional reduction in blood pressure after cholesterol-lowering treatment by statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril)

被引：112

作者：

Spósito, AC ^{[1
]}

Mansur, AP ^{[1
]}

Coelho, OR ^{[1
]}

Nicolau, JC ^{[1
]}

Ramires, JAF ^{[1
]}

机构：

[1] Univ Sao Paulo, Sch Med, Inst Heart InCor, Sao Paulo, Brazil

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 83卷 / 10期

关键词：

D O I：

10.1016/S0002-9149(99)00132-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Blood pressure (BP) reduction was compared between patients receiving angiotensin-converting enzyme inhibitors alone and patients receiving these medications plus statins after 3 months of dietary intervention. Although BP was similarly reduced at week 4, the statin-treated group had a greater reduction in BP and total cholesterol levels at week 16, suggesting a synergistic effect between cholesterol lowering with statins and angiotensin-converting enzyme inhibitor treatment for hypertensive patients.

引用

页码：1497 / +

页数：4

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