The effect of acidosis on the ECG of the rat heart

被引：24

作者：

Aberra, A

Komukai, K

Howarth, FC

Orchard, CH

机构：

[1] United Arab Emirates Univ, Fac Med & Hlth Sci, Al Ain, U Arab Emirates

[2] Univ Leeds, Sch Biomed Sci, Leeds LS2 9NL, W Yorkshire, England

[3] Univ Addis Ababa, Fac Med, Addis Ababa, Ethiopia

来源：

EXPERIMENTAL PHYSIOLOGY | 2001年 / 86卷 / 01期

关键词：

D O I：

10.1113/eph8602051

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

We have investigated the effect of acidosis on the ECG in isolated rat heart to determine whether acidosis has marked effects on the ECG, and have used pharmacological agents to investigate possible mechanisms whereby acidosis alters the ECG. Acidosis produced a marked decrease in heart rate and an increase in P-R interval with little apparent effect on the duration of the QRS complex. The effects of acidosis did not appear to be due to acidosis-induced changes in transmitter release from severed autonomic nerve terminals within the heart.

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页码：27 / 31

页数：5

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