Laboratory diagnosis of acute myocardial injury

被引：25

作者：

Melanson, SF ^{[1
]}

Tanasijevic, MJ ^{[1
]}

机构：

[1] Brigham & Womens Hosp, Dept Pathol, Div Clin Labs, Boston, MA 02115 USA

来源：

CARDIOVASCULAR PATHOLOGY | 2005年 / 14卷 / 03期

关键词：

myocardial injury; laboratory diagnosis; cardiac markers;

D O I：

10.1016/j.carpath.2005.01.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Considerable effort by clinicians and scientists focuses on the utility of biomarkers to prevent, diagnose and manage adverse cardiac events as well as provide information on a specific patient's underlying pathology. Although troponins I and T (Tnl and TnT) are cardiac specific markers that yield diagnostic and prognostic value in patients with myocardial injury, troponins cannot be utilized in all clinical settings. Troponins have limited utility for the diagnosis of early ischemia and preoperative myocardial infarction. Troponin T also lacks specificity in patients with renal failure. New markers, such as ischemia modified albumin (IMA) and CD40 ligand, and new technologies, such as proteomics, are under investigation to advance our knowledge of heart disease. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：156 / 161

页数：6

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