Rate of neuronal fallout in a transsynaptic cerebellar model

被引：25

作者：

Triarhou, LC

机构：

[1] Indiana Univ, Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA

[2] Indiana Univ, Sch Med, Program Med Neurobiol, Indianapolis, IN 46202 USA

来源：

BRAIN RESEARCH BULLETIN | 1998年 / 47卷 / 03期

关键词：

cerebellum; Purkinje cell; granule cell; neurological mutant mice; mathematical models; exponential decay;

D O I：

10.1016/S0361-9230(98)00076-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Quantitative analyses of transsynaptic granule cell death subsequent to the genetically determined degeneration of Purkinje cells in the cerebellum of pcd/pcd mutant mice show that granule neuron fallout follows a typical mathematical pattern of elemental decay, Biological and theoretical connotations are discussed in light of the empirical observations and a simulation model. (C) 1998 Elsevier Science Inc.

引用

页码：219 / 222

页数：4

共 23 条

[1]

[Anonymous], 1981, Statistical Tables

[2]

Burnet Macfarlane, 1978, ENDURANCE LIFE IMPLI

[3] STRUCTURAL AND QUANTITATIVE STUDIES ON THE NORMAL C3H AND LURCHER MUTANT MOUSE [J].