Protein printing with an atomic force sensing nanofountainpen

被引：60

作者：

Taha, H ^{[1
]}

Marks, RS

Gheber, LA

Rousso, I

Newman, J

Sukenik, C

Lewis, A

机构：

[1] Hebrew Univ Jerusalem, Div Appl Phys, Jerusalem, Israel

[2] Ben Gurion Univ Negev, Inst Appl Biosci, Dept Biotechnol Engn, IL-84105 Beer Sheva, Israel

[3] MIT, Whitehead Inst Biomed Res, Dept Biol, Cambridge, MA 02142 USA

[4] Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA 94143 USA

[5] Bar Ilan Univ, Dept Chem, Ramat Gan, Israel

来源：

APPLIED PHYSICS LETTERS | 2003年 / 83卷 / 05期

关键词：

D O I：

10.1063/1.1594844

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We demonstrate the direct printing of proteins on a surface using a cantilevered nanopipette as the probe of a scanned probe microscope. Protein features as small as similar to200 nm were directly delivered through the similar to100 nm aperture of the nanopipette by simply contacting the probe with any surface. This allows for the direct connection of this methodology to standard separation techniques so that multiple proteins can be printed through one nanopipette at different locations in ambient conditions. (C) 2003 American Institute of Physics.

引用

页码：1041 / 1043

页数：3