Seronegative and seropositive RA: alike but different?

被引:62
作者
Ajeganova, Sofia [1 ]
Huizinga, Tom W. J. [2 ]
机构
[1] Karolinska Univ Hosp Huddinge, Karolinska Inst, Dept Med, Rheumatol Unit R92, S-14186 Stockholm, Sweden
[2] Leiden Univ, Med Ctr, Dept Rheumatol, NL-2300 RC Leiden, Netherlands
关键词
RHEUMATOID-ARTHRITIS; ACPA-STATUS;
D O I
10.1038/nrrheum.2014.194
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
The presence or absence of autoantibodies in patients with rheumatoid arthritis (RA) can guide clinical practice, but the role of autoantibody status in 'real life' is unclear. A cohort study from Canada provides clinical perspective on the presentation, prognosis and efficacy of treatment of patients with autoantibody-negative RA.
引用
收藏
页码:9 / 10
页数:2
相关论文
共 10 条
[1]
Barra L., J RHEUMATOL
[2]
Should We Redefine Treatment Targets in Rheumatoid Arthritis? Low Disease Activity Is Sufficiently Strict for Patients Who Are Anticitrullinated Protein Antibody-negative [J].
de Punder, Yvonne M. R. ;
Hendrikx, Jos ;
den Broeder, Alfons A. ;
Pascual, Elia Valls ;
van Riel, Piet L. ;
Fransen, Jaap .
JOURNAL OF RHEUMATOLOGY, 2013, 40 (08) :1268-1274
[3]
Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes? [J].
de Rooy, Diederik P. C. ;
Willemze, Annemiek ;
Mertens, Bart ;
Huizinga, Tom W. J. ;
Van der Helm-van Mil, Annette H. M. .
ARTHRITIS RESEARCH & THERAPY, 2011, 13 (05)
[4]
ACPA-positive and ACPA-negative rheumatoid arthritis differ in their requirements for combination DMARDs and corticosteroids: secondary analysis of a randomized controlled trial [J].
Seegobin, Seth D. ;
Ma, Margaret H. Y. ;
Dahanayake, Chanaka ;
Cope, Andrew P. ;
Scott, David L. ;
Lewis, Cathryn M. ;
Scott, Ian C. .
ARTHRITIS RESEARCH & THERAPY, 2014, 16 (01)
[5]
Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage [J].
Shi, Jing ;
Knevel, Rachel ;
Suwannalai, Parawee ;
van der Linden, Michael P. ;
Janssen, George M. C. ;
van Veelen, Peter A. ;
Levarht, Nivine E. W. ;
van der Helm-van Mil, Annette H. M. ;
Cerami, Anthony ;
Huizinga, Tom W. J. ;
Toes, Rene E. M. ;
Trouw, Leendert A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (42) :17372-17377
[6]
Autoimmunity in rheumatoid arthritis: different antigens-common principles [J].
Trouw, L. A. ;
Huizinga, Tom W. J. ;
Toes, Rene E. M. .
ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 :132-136
[7]
The association of treatment response and joint damage with ACPA-status in recent-onset RA: a subanalysis of the 8-year follow-up of the BeSt study [J].
van den Broek, M. ;
Dirven, L. ;
Klarenbeek, N. B. ;
Molenaar, T. H. E. ;
Han, K. H. ;
Kerstens, P. J. S. M. ;
Huizinga, T. W. J. ;
Dijkmans, B. A. C. ;
Allaart, C. F. .
ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (02) :245-248
[8]
Sustained drug-free remission in rheumatoid arthritis after DAS-driven or non-DAS-driven therapy: a comparison of two cohort studies [J].
van der Woude, Diane ;
Visser, Karen ;
Klarenbeek, Naomi B. ;
Ronday, H. Karel ;
Peeters, Andre J. ;
Kerstens, Pit J. S. M. ;
Dijkmans, Ben A. C. ;
Huizinga, Tom W. J. ;
van der Helm-van Mil, Annette H. M. ;
Allaart, Cornelia F. .
RHEUMATOLOGY, 2012, 51 (06) :1120-1128
[9]
Remission induction therapy with methotrexate and prednisone in patients with early rheumatoid and undifferentiated arthritis (the IMPROVED study) [J].
Wevers-de Boer, Kirsten ;
Visser, Karen ;
Heimans, Lotte ;
Ronday, H. Karel ;
Molenaar, Esmeralda ;
Groenendael, J. Hans L. M. ;
Peeters, Andre J. ;
Westedt, Marie-Louise ;
Collee, Gerard ;
de Sonnaville, Peter B. J. ;
Grillet, Bernard A. M. ;
Huizinga, Tom W. J. ;
Allaart, Cornelia F. .
ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (09) :1472-1477
[10]
The influence of ACPA status and characteristics on the course of RA [J].
Willemze, Annemiek ;
Trouw, Leendert A. ;
Toes, Rene E. M. ;
Huizinga, Tom W. J. .
NATURE REVIEWS RHEUMATOLOGY, 2012, 8 (03) :144-152