Mechanisms of acute and chronic nephrotoxicity from immunosuppressive drugs

被引:19
作者
Bennett, WM
机构
关键词
D O I
10.3109/08860229609052816
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Cyclosporine and related compounds have dramatically improved the short-term success of solid organ transplantation This paper outlines the pathophysiologic mechanisms of the nephrotoxicity of these compounds, highlighting relevant clinical and experimental work. It is hoped that as further understanding of these mechanisms evolves, rational therapeutic strategies will be available.
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页码:453 / 460
页数:8
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