Enzymes inhibitory constituents from Buddleja crispa

被引：9

作者：

Ahmad, I

Malik, A ^{[1
]}

Afza, N

Anis, I

Fatima, I

Nawaz, SA

Tareen, RB

Choudhary, MI

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan

[2] Pakistan Council Sci & Ind Res, Pharmaceut Res Ctr, Karachi, Pakistan

[3] Univ Baluchistan, Dept Bot, Baluchistan, Pakistan

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2005年 / 60卷 / 03期

关键词：

Buddleja crispa; buddlejaceac; steroid galactoside; aryl esters; enzyme inhibition;

D O I：

10.1515/znb-2005-0319

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学]; 081704 [应用化学];

摘要：

Steroidal galactoside 1 and aryl esters 2 and 3 have been isolated from Buddleja crispa, along with ginipin 4, gardiol 5, 1-heptacosanol 6, and methyl benzoate 7, isolated for the first time from this species. The structures of all of the compounds were determined by spectroscopic techniques and chemical studies. The steroidal galactoside 1 is an inhibitor of lipoxygenase. Compounds 1-3 displayed inhibitory activity against butyrylcholinesterse, while compounds 2 and 3 further showed inhibition against acetylcholinesterase.

引用

页码：341 / 346

页数：6

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