Influence of bacterial strains on bone infection

被引:33
作者
Cordero, J
Munuera, L
Folgueira, MD
机构
[1] HOSP LA PAZ,DEPT ORTHOPAED SURG,MADRID,SPAIN
[2] HOSP LA PAZ,DEPT MICROBIOL,MADRID,SPAIN
关键词
D O I
10.1002/jor.1100140423
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Experiments were performed on 120 rabbits to compare the probability of infection after bone surgery without an implant, with polymethylmethacrylate, and with bone autografts. Staphylococcus aureus phage type 94/96, isolated from a human osteomyelitis, was instilled into the intramedullar cavity after reaming of the femoral canal and before insertion of the implant. The different 50% infective doses were determined for each of the groups for comparative purposes. The bacterial concentrations required to produce infection in femora without an implant were two times less than those necessary in femora implanted with polymethylmethacrylate. The bone graft required bacterial concentrations nine times less than those necessary to infect femora containing polymethylmethacrylate and four times less than those required to infect femora without an implant. The results presented here confirm that the susceptibility to infection in orthopaedic surgery is not only material dependent but also bacteria dependent.
引用
收藏
页码:663 / 667
页数:5
相关论文
共 37 条
[1]  
[Anonymous], CLIN ORTHOPAEDICS
[2]  
ARIZONO T, 1992, ACTA ORTHOP SCAND, V63, P661
[3]  
BACH BR, 1985, CLIN ORTHOPAEDICS, V193, P146
[4]   RELEASE OF GENTAMICIN FROM ACRYLIC BONE-CEMENT - ELUTION AND DIFFUSION STUDIES [J].
BAKER, AS ;
GREENHAM, LW .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1988, 70A (10) :1551-1557
[5]  
BARTH E, 1989, T ORTHOP RES SOC, V14, P558
[6]   THE INFECTED KNEE ARTHROPLASTY - A 6-YEAR FOLLOW-UP OF 357 CASES [J].
BENGTSON, S ;
KNUTSON, K .
ACTA ORTHOPAEDICA SCANDINAVICA, 1991, 62 (04) :301-311
[7]  
BLISS DG, 1985, CLIN ORTHOPAEDICS, V199, P207
[8]  
BOOTH RE, 1989, CLIN ORTHOP RELAT R, V248, P57
[9]  
BURWELL RG, 1985, CLIN ORTHOP RELAT R, V197, P141
[10]   INFECTION AT THE SITE OF IMPLANTED MATERIALS WITH AND WITHOUT PREADHERED BACTERIA [J].
CHANG, CC ;
MERRITT, K .
JOURNAL OF ORTHOPAEDIC RESEARCH, 1994, 12 (04) :526-531