A sesquiterpene lactone glucoside from Ixeris denticulata f. pinnatipartita

被引：29

作者：

Ma, JY

Wang, ZT

Xu, LS

Xu, GJ

机构：

[1] Shanghai Med Univ, Pharmanex Shanghai R&D Ctr, Shanghai 200032, Peoples R China

[2] China Pharmaceut Univ, Dept Pharmacognosy, Nanjing 210038, Peoples R China

来源：

PHYTOCHEMISTRY | 1999年 / 50卷 / 01期

关键词：

Ixeris denticulata f. pinnatipartita Kitag; Compositae; Ixerin Y; luteolin-7-O-glucoside; luteolin-7-O-glucuronide-6 '-methyl ester; cytotoxicity;

D O I：

10.1016/S0031-9422(98)00452-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An extract from the entire Ixriss denticulata f. pinnatipartita plant afforded the guaianolide sesquiterpene lactone glucoside, 8 beta,15-dihydroxy-1(10),3,11(13)-guaiatrien-12,6-olide-15-O-glucopyranoside, along with the known flavonoids luteolin-7-O-glucoside and luteolin-7-O-glucuronide-6'-methyl ester; their structures were determined by spectroscopic methods. Ixerin Y inhibited the growth of human breast cancer MCF7 and MDA468 cell lines. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：113 / 115

页数：3

共 15 条

[1]

ADEGAWA S, 1985, CHEM PHARM BULL, V33, P4906

[2]

ASADA H, 1984, CHEM PHARM BULL, V32, P3036

[3]

ASADA H, 1984, CHEM PHARM BULL, V32, P1724

[4]

ASADA H, 1984, CHEM PHARM BULL, V32, P3403

[5] LARVAL GROWTH-INHIBITORS FROM SPECIES OF PRTHENIUM (ASTERACEAE) [J].

ISMAN, MB ;

RODRIGUEZ, E .

PHYTOCHEMISTRY, 1983, 22 (12) :2709-2713

[6]

KITAGOWA L, 1939, FLORA MASHURIA, P454

[7] SESQUITERPENE LACTONES FROM LACTUCA-LACINIATA [J].

NISHIMURA, K ;

MIYASE, T ;

UENO, A ;

NORO, T ;

KUROYANAGI, M ;

FUKUSHIMA, S .

PHYTOCHEMISTRY, 1986, 25 (10) :2375-2379

[8]

NISHIMURA K, 1985, CHEM PHARM BULL, V33, P3361

[9] ANT-REPELLENT SESQUITERPENE LACTONES FROM EUPATORIUM-QUADRANGULARAE [J].

OKUNADE, AL ;

WIEMER, DF .

PHYTOCHEMISTRY, 1985, 24 (06) :1199-1201

[10]

SETO M, 1986, CHEM PHARM BULL, V34, P4170

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