DNA replication: Partners in the Okazaki two-step

被引：45

作者：

MacNeill, SA ^{[1
]}

机构：

[1] Univ Edinburgh, Inst Cell & Mol Biol, Wellcome Trust Ctr Cell Biol, Edinburgh EH9 3JR, Midlothian, Scotland

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 20期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0960-9822(01)00500-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

引用

页码：R842 / R844

页数：3

共 14 条

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