Chloride finds its place in the transport cycle

被引：7

作者：

Amara, Susan G. ^{[1
]}

机构：

[1] Univ Pittsburgh, Sch Med, Dept Neurobiol, Pittsburgh, PA 15261 USA

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2007年 / 14卷 / 09期

关键词：

D O I：

10.1038/nsmb0907-792

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Neurotransmitter: sodium symporters, which use sodium gradients for the coupled uptake of sodium and neurotransmitters during synaptic transmission, often display a chloride dependence. New data from two separate groups identify the chloride- binding site for this family of symporters and suggest that the chloride charge facilitates sodium binding and substrate transport.

引用

页码：792 / 794

页数：5

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