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Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy

被引：237
作者：
Arutyunyan, Irina [1 ]
Elchaninov, Andrey [2 ]
Makarov, Andrey [1 ]
Fatkhudinov, Timur [1 ,2 ]
机构：
[1] Minist Healthcare Russian Federat, Res Ctr Obstet Gynecol & Perinatol, 4 Oparin St, Moscow 117997, Russia
[2] Pirogov Russian Natl Res Med Univ, Minist Healthcare Russian Federat, 1 Ostrovitianov St, Moscow 117997, Russia
来源：
STEM CELLS INTERNATIONAL | 2016年 / 2016卷
基金：
俄罗斯科学基金会;
关键词：
STROMAL CELLS; BONE-MARROW; IN-VITRO; GENE-EXPRESSION; MITOCHONDRIAL TRANSFER; MYOCARDIAL-INFARCTION; IMMUNE PROPERTIES; DIFFERENTIATION; TISSUE; TRANSPLANTATION;
D O I：
10.1155/2016/6901286
中图分类号：
Q813 [细胞工程];
学科分类号：
100113 [医学细胞生物学];
摘要：
The paper presents current evidence on the properties of human umbilical cord-derived mesenchymal stem cells, including origin, proliferative potential, plasticity, stability of karyotype and phenotype, transcriptome, secretome, and immunomodulatory activity. A review of preclinical studies and clinical trials using this cell type is performed. Prospects for the use of mesenchymal stem cells, derived from the umbilical cord, in cell transplantation are associated with the need for specialized biobanking and transplant standardization criteria.
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页数：17
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