Metforinin lactic acidosis, acute renal failure and rofecoxib

被引：18

作者：

Price, G ^{[1
]}

机构：

[1] Victoria Hosp, Dept Anaesthesia, Kirkcaldy, Fife, Scotland

来源：

BRITISH JOURNAL OF ANAESTHESIA | 2003年 / 91卷 / 06期

关键词：

complications; acute renal failure; non-steroidal anti-inflammatory drugs;

D O I：

10.1093/bja/aeg255

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

A patient with acute renal failure associated with lactic acidosis as a result of concurrent treatment with metformin is described. Rofecoxib may have been a precipitating factor. The risk of renal failure with the use of traditional NSAIDs is well known. However, what is less well appreciated is the role that the COX 2 inhibitors may play in the development of renal failure which, when it occurs in a patient on metformin, can lead to a potentially disastrous outcome.

引用

页码：909 / 910

页数：2

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