Recombination: Holliday junction resolution and crossover formation

被引：38

作者：

Heyer, WD ^{[1
]}

机构：

[1] Univ Calif Davis, Div Biol Sci, Microbiol Sect, Davis, CA 95616 USA

[2] Univ Calif Davis, Div Biol Sci, Sect Mol & Cellular Biol, Davis, CA 95616 USA

[3] Univ Calif Davis, Div Biol Sci, Ctr Genet & Dev, Davis, CA 95616 USA

来源：

CURRENT BIOLOGY | 2004年 / 14卷 / 02期

关键词：

D O I：

10.1016/j.cub.2003.12.043

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The heterodimeric nuclease Mus81-Eme1 has been proposed to be a Holliday junction resolvase and has now been found to be responsible for nearly all meiotic crossovers in fission yeast. The intriguing substrate preference of this enzyme for nicked Holliday junctions opens the possibility that crossover formation may not always involve double Holliday junctions.

引用

页码：R56 / R58

页数：3

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