The squalestatins: Synthesis of C-4 carboxamide derivatives

被引：4

作者：

Chan, C

Scicinski, JJ

Srikantha, ARP

Watson, NS

机构：

[1] GlaxoWellcome R. and D., Medicines Research Centre, Stevenage, Hertfordshire, SG1 2NY, Gunnels Wood Road

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(96)02049-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of squalestatin S1 C-4 carboxamide, 2, as well as related C-4 amides and C-4 hydroxymethyl derivatives possessing a C-3 hydroxymethyl group (15 and 19) together with their SQS inhibitory activities are presented. Copyright (C) 1996 Elsevier Science Ltd

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收藏

页码：8925 / 8928

页数：4

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