Biological agent detection and identification by the block II chemical biological mass spectrometer

被引：16

作者：

Griest, WH ^{[1
]}

Wise, MB ^{[1
]}

Hart, KJ ^{[1
]}

Lammert, SA ^{[1
]}

Thompson, CV ^{[1
]}

Vass, AA ^{[1
]}

机构：

[1] Oak Ridge Natl Lab, Div Chem & Analyt Sci, Oak Ridge, TN 37831 USA

来源：

FIELD ANALYTICAL CHEMISTRY AND TECHNOLOGY | 2001年 / 5卷 / 04期

关键词：

biological warfare agents; biodetection and identification; fieldable ion trap mass spectrometer; thermal hydrolysis methylation;

D O I：

10.1002/fact.1019

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The Block II Chemical Biological Mass Spectrometer (CBMS) detects and identifies both chemical and biological warfare agents. Biodetection is based upon respirable particle collection by an opposed-let virtual impactor, liberation of derivatized biomarkers by thermolysis-methylation and their analysis by direct-sampling ion trap mass spectrometry in the full-scan chemical ionization mode. Results from laboratory and field trials demonstrate the capability of the Block II CBMS for biodetection and identification. (C) 2001 John Wiley & Sons, Inc.

引用

页码：177 / 184

页数：8

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